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According to another embodiment, the composition further comprises at least one botanical extract containing a therapeutic amount of a botanical active ingredient, wherein the botanical extract is selected from the group consisting of: (f) a Centella asiatica (Gotu kola) extract comprising at least one Centella asiatica active ingredient

For instance, it may affect the metabolism of drugs that are substrates of the cytochrome P450 enzyme system, potentially altering their efficacy or toxicity